See Google Scholar for an chronological listing
Virus discovery and evolution
Hojat Ansari M, Staubach F, Alacatli N, Obbard DJ (bioRxiv) A diverse gut virome from Drosophila melanogaster [bioRxiv from 19th March 2024]
Wallace MA, Obbard DJ (2024) Naturally occurring viruses of Drosophila reduce offspring number and lifespan Proceedings of the Royal Society B 291:20240518 [bioRxiv from 5th September 2023]
Kuyateh O, Obbard DJ (2023) Viruses in laboratory Drosophila and their impact on host gene expression Viruses 15(9) 1849 [bioRxiv from 10th July 2023]
Wallace MA, Coffman KA, Gilbert C, Ravindran S, Albery GF, Abbott J, Argyridou E, Bellosta P, Betancourt AJ, Colinet H, Eric K, Glaser-Schmitt A, Grath S, Jelic M, Kankare M, Kozeretska I, Loeschcke V, Montchamp-Moreau C, Ometto L, Sebnem Onder B, Orengo DJ, Parsch J, Pascual M, Patenkovic A, Puerma E, Ritchie MG, Rota-Stabelli O, Fristrup Schou M, Serga SV, Stamenkovic-Radak M, Tanaskovic M, Savic Veselinovic M, Vieira J, Vieira CP, Kapun M, Flatt T, Gonzalez J, Staubach F, Obbard DJ (2021) The discovery, distribution and diversity of DNA viruses associated with Drosophila melanogaster in Europe Virus Evolution veab031 [bioRxiv from 16th October 2020]
Pascall DJ, Tinsley MC, Clark BL, Obbard DJ, Wilfert L (2021). Virus prevalence and diversity across a wild bumblebee community Frontiers in Microbiology [bioRxiv from 7th January 2021]
Pascall DJ, Hadfield JD, Tinsley MC, Obbard DJ, Wilfert L (bioRxiv). Host evolutionary history predicts virus prevalence across bumblebee species [bioRxiv from 17th December 2018]
Obbard DJ, Shi M, Roberts KE, Longdon B, Dennis AB (2020) A new lineage of segmented RNA viruses infecting animals Virus Evolution 6(1):vez061 [bioRxiv from 21st August 2019]
Palmer WH, Joosten J, Overheul GJ, Jansen PW, Vermeulen M, Obbard DJ, van Rij RP (2019) Induction and suppression of NF-{kappa}B signalling by a DNA virus of Drosophila Journal of Virology 93:3 e01443-18 [bioRxiv from 29th June 2018]
Palmer WH, Medd NC, Beard PM, Obbard DJ (2018) Isolation of a natural DNA virus of Drosophila melanogaster, and characterisation of host resistance and immune responses PLOS Pathogens 14(6):e1007050. [bioRxiv from 7th November 2017] [Featured in TWiV 522]
Medd NC, Fellous S, Waldron FM, Nakai M, Xuereb A, Cross JV, Obbard DJ (2018) The virome of Drosophila suzukii, an invasive pest of soft fruit Virus Evolution, Volume 4(1): vey009, [bioRxiv from 18th September 2017]
Longdon B, Day JP, Schulz N, Leftwich PT, de Jong MA, Breuker CJ, Gibbs M, Obbard DJ, Wilfert L, Smith SCL, McGonigle JE, Houslay TM, Wright L, Livraghi L, Evans LC, Friend LA, Chapman T, JVontas J, Kambouraki N, Jiggins FM (2017) Vertically transmitted rhabdoviruses are found across three insect families and have dynamic interactions with their hosts Proceedings of the Royal Society B.284: 20162381 [bioRxiv from 31st October 2016]
Webster CL, Longdon B, Lewis SH,Obbard DJ (2016). Twenty five new viruses associated with the Drosophilidae (Diptera) Evolutionary Bioinformatics 2016:Suppl. 2 13-25 [bioRxiv from 29th February 2016] Supporting information
Longdon B, Murray GGR, Palmer WJ, Day JP, Parker DJ, Welch JJ, Obbard DJ, Jiggins FM (2015). The evolution, diversity, and host associations of rhabdoviruses Virus Evolution 1(1): vev014 [bioRxiv from 5th June 2015]
Webster CL, Waldron FM, Robertson S, Crowson D, Ferrari G, Quintana JF, Brouqui J-M, Bayne EH, Longdon B, Buck AH, Lazzaro BP, Akorli J, Haddrill PR, Obbard DJ, (2015) The discovery, distribution, and evolution of viruses associated with Drosophila melanogaster PLoS Biology 13(7): e1002210. [bioRxiv from 18th June 2015] [Featured in TWiV 348] Opinion
Longdon B, Hadfield JD, Webster CL, Obbard DJ, Jiggins FM (2011) Host phylogeny determines viral persistence and replication in novel hosts PLoS Pathogens 7(9):e1002260
Longdon B, Wilfert L, Osei-Poku J, Cagney H, Obbard DJ, Jiggins FM (2011) Host-switching by a vertically transmitted rhabdovirus in Drosophila Biology Letters 7(5):747-750
Longdon B, Wilfert L, Obbard DJ, Jiggins FM (2011) Rhabdoviruses in two species of Drosophila: vertical transmission and a recent sweep Genetics 188:1 141-150
Longdon B, Obbard DJ, Jiggins FM (2010) Sigma viruses from three species of Drosophila form a major new clade in the rhabdovirus phylogeny. Proceedings of the Royal Society B 277:35-44
Carpenter JA, Obbard DJ, Maside X, Jiggins FM, (2007). The recent spread of a vertically transmitted virus through populations of Drosophila melanogaster. Molecular Ecology 16: 3947-3954
Drosophila evolution
Nunez JCB, Coronado-Zamora M, Gautier M, Kapun M, Steindl S, Ometto L, Hoedjes KM, Beets J, Wiberg RAW, Mazzeo GR, Bass DJ, Radionov D, Kozeretska I, Zinchenko M, Protsenko O, Serga S, Amor-Jimenez C, Casillas S, Sanchez-Gracia A, Patenkovic A, Glaser-Schmitt A, Barbadilla A, Buendia-Ruiz A J, Clelia Bertelli A, Kiss B, Sebnem Onder B, Roldan Matrin B, Wertheim B, Deschamps C, Arboleda-Bustos CE, Tinedo C, Feller C, Schlotterer C, Lawler C, Fricke C, Vieira C P, Vieira C, Obbard DJ, Orengo D, Vela D, Amat E, Loreto E, Kerdaffrec E, Durmaz Mitchell E, Puerma E, Staubach F, Camus F, Colinet H, Hrcek J, Sorensen JG, Abbott J, Torro J, Parsch J, Vieira J, Luis Olmo J, Khfif K, Wojciechowski K, Madi-Ravazzi L, Kankare M, Schou MF, Ladoukakis M, Gomez-Julian MJ, Espinosa-Jimenez ML, Garcia-Guerreiro MP, Parakatselaki M, Savic Veselinovic M, Tanaskovic M, Stamenkovic-Radak M, Paris M, Pascual M, Ritchie M G, Rera M, Jelic M, Hojat Ansari M, Rakic M, Merenciano M, Hernandes N, Gora N, Rode N, Rota-Stabelli O, Sepulveda P, Gibert P, Carazo P, Kohlmeier P, Erickson PA, Vitalis R, Torres R, Guirao-Rico S, Ramos-Onsins SE, Castillo S, Paulo TF, Tyukmaeva V, Alonso Z, Alatortsev V, Pasyukova E, Mukha D, Petrov D, Schmidt P, Flatt T, Bergland AO, Gonzalez J (biorxiv) Footprints of worldwide adaptation in structured populations of D. melanogaster through the expanded DEST 2.0 genomic resource [bioRxiv from 11th November 2024]
Kim BY, Gellert HR, Church SH, Suvorov A, Anderson SS, Barmina O, Beskid SG, Comeault AA, Crown KN, Diamond SE, Dorus S, Fujichika T, Hemker JA, Hrcek J, Kankare M, Katoh T, Magnacca KN, Martin RA, Matsunaga T, Medeiros MJ, Miller DE, Pitnick S, Simoni S, Steenwinkel TE, Schiffer M, Syed ZA, TakahashiA ,Wei KH-C, Yokoyama T, Eisen MB, Kopp A, Matute D, Obbard DJ, O'Grady PM, Price DK, Toda MJ, Werner T, Petrov DA (biorxiv) Single-fly genome assemblies fill major phylogenomic gaps across the Drosophilidae Tree of Life PLOS Biology 22(7): e3002697 [bioRxiv from 2nd Oct 2023]
Wang Y, McNeil P, Abdulazeez R, Pascual M, Johnston SE, Keightley PD, Obbard DJ (2023) Variation in mutation, recombination, and transposition rates in Drosophila melanogaster and Drosophila simulans Genome Research 33:587-598 [bioRxiv from 14th September 2022]
Kapun M, Nunez JCB, Bogaerts-Marquez M, Murga-Moreno J, Paris M, Outten J, Coronado-Zamora M, Tern C, Rota-Stabelli O, Garcia Guerreiro MP, Casillas S, Orengo DJ, Puerma E, Kankare M, Ometto L, Loeschcke V, Onder BS, Abbott JK, Schaeffer SW, Rajpurohit S, Behrman EL, Schou MF, Merritt TJS, Lazzaro BP, Glaser-Schmitt A, Argyridou E, Staubach F, Wang Y, Tauber E, Serga SV, Fabian DK, Dyer KA, Wheat CW, Parsch J, Grath S, Veselinovic MS, Stamenkovic-Radak M, Jelic M, Buendia-Ruiz AJ, Gomez-Julian MJ, Espinosa-Jimenez ML, Gallardo-Jimenez FD, Patenkovic A, Eric K, Tanaskovic M, Ullastres A, Guio L, Merenciano M, Guirao-Rico S, Horvath V, Obbard DJ, Pasyukova E, Alatortsev VE, Vieira CP, Vieira J, Torres JR, Kozeretska I, Maistrenko OM, Montchamp-Moreau C, Mukha DV, Machado HE, Barbadilla A, Petrov D, Schmidt P, Gonzalez J, Flatt T, Bergland AO (2021) Drosophila Evolution over Space and Time (DEST) - A New Population Genomics Resource [bioRxiv from 1st Feb 2021]
Kapun M, Barron MG, Staubach F, Obbard DJ, Wiberg RAW, Vieira J, Goubert C, Rota-Stabelli O, Kankare M, Bogaerts-Marquez M, Haudry A, Waidele L, Kozeretska I, Pasyukova EG, Loeschcke V, Pascual M, Vieira CP, Serga S, Montchamp-Moreau C, Abbott J, Gibert P, Porcelli D, Posnien N, Sanchez-Gracia A, Grath S, Sucena E, Bergland AO, Pilar Garcia Guerreiro M, Sebnem Onder B, Argyridou E, Guio L, Fristrup Schou M, Deplancke B, Vieira C, Ritchie MG, Zwaan BJ, Tauber E, Orengo DJ, Puerma E, Aguade M, Schmidt PS, Parsch J, Betancourt AJ, Flatt T, Gonzalez J (2020) Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses [bioRxiv from 3rd May 2018]
Obbard DJ, Maclennan J, Kim K-W, Rambaut A, O'Grady PM, Jiggins FM, (2012) Estimating divergence dates and substitution rates in the Drosophila phylogeny. Molecular Biology and Evolution 29 (11): 3459-3473
Obbard DJ, Welch JJ, Kim K-W, Jiggins FM (2009) Quantifying Adaptive Evolution in the Drosophila Immune System. PLoS Genetics 5(10): e1000698.
Bangham J, Obbard, DJ, Kim K-W, Haddrill PR, Jiggins FM, (2007) The age and evolution of an antiviral resistance mutation in Drosophila melanogaster. Proceedings of the Royal Society B 274:2027-2034
Evolution of RNAi
Crysnanto D, Obbard DJ, (2019). Widespread gene duplication and adaptive evolution in the RNA interference pathways of the Drosophila obscura group BMC Evolutionary Biology 19(99) [bioRxiv from 29th September 2018]
Waldron FM, Stone GS, Obbard DJ, (2018). Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes PLoS Genet 14(7): e1007533 [bioRxiv from 21st July 2017]
Palmer WH, Hadfield JD, Obbard DJ, (2018). RNA interference pathways display high rates of adaptive protein evolution across multiple invertebrates Genetics 208(4) pp1585-1599. [bioRxiv from 23rd June 2017]
Lewis SH, Webster CL, Salmela H, Obbard DJ, (2016). Repeated duplication of Argonaute2 is associated with strong selection and testis specialization in Drosophila Genetics 204: 757-769 [bioRxiv from 1st April 2016]
Palmer WH, Obbard DJ, (2016). Variation and Evolution in the Glutamine-Rich Repeat Region of Drosophila Argonaute-2 Genes|Genomes|Genetics G3 g3.116.031880; Early Online June 17, 2016 [bioRxiv from 14th April 2016]
Lewis SH, Salmela H, Obbard DJ, (2016). Duplication and diversification of Dipteran Argonaute genes, and the evolutionary divergence of Piwi and Aubergine Genome Biology and Evolution 8 (3): 507-518.
van Mierlo JT, Overheul GJ, Obadia B, van Cleef KWR, Webster CL, Saleh M-C, Obbard DJ, van Rij RP (2014) Novel Drosophila viruses encode host-specific suppressors of RNAi PLoS Pathogens 10(7):e1004256
Schnettler E, Tykalova H, Watson M, Sharma M, Sterken MG, Obbard DJ, Lewis SH, McFarlane M, Bell-Sakyi L, Barry G, Weisheit S, Best SM, Kuhn RJ, Pijlman GP, Chase-Topping ME, Gould EA, Grubhoffer L, Fazakerley JK, Kohl A (2014) Induction and suppression of tick cell antiviral RNAi responses by tick-borne flaviviruses Nucleic Acids Research
Murray GGR, Kosakovsky Pond SL Obbard DJ (2013) Suppressors of RNAi from plant viruses are subject to episodic positive selection Proc. R. Soc. B. 2013 280 20130965
Obbard DJ, Jiggins FM, Bradshaw NJ, Little TJ (2011) Recent and recurrent selective sweeps of the antiviral RNAi gene Argonaute-2 in three species of Drosophila. Molecular Biology and Evolution 28(2): 1043-1056
Obbard DJ, Jiggins FM, Halligan DL, Little TJ (2006). Natural selection drives extremely rapid evolution in antiviral RNAi genes. Current Biology 16: 580-585.
Daphnia population genetics
Fields P, McTaggart S, Reisser CMO, Haag C, Palmer WH, Little TJ, Ebert D, Obbard DJ (2022) Population-genomic analysis identifies a low rate of global adaptive fixation in the proteins of the cyclical parthenogen Daphnia magna Molecular Biology and Evolution, msac048
Fields PD, Obbard DJ, McTaggart SJ, Galimov Y, Little TJ, Ebert D (2018) Mitogenome phylogeographic analysis of a planktonic crustacean Molecular Phylogenetics and Evolution 129:138-148 or [preprint]
McTaggart SJ, Obbard DJ, Conlon C, Little TJ, (2012). Immune genes undergo more adaptive evolution than non-immune system genes in Daphnia pulex. BMC Evolutionary Biology 12:63
Killick SC, Obbard DJ, West SA, Little TJ (2008). Parasitism and breeding system variation in North American populations of Daphnia pulex. Ecological Research 23(1): 235-240
Anopheles population genetics
Smith PH, Mwangi JM, Afrane YA, Yan G, Obbard DJ, Ranford-Cartwright LC, Little TJ (2011) Alternative splicing of the Anopheles gambiae Dscam gene in diverse Plasmodium falciparum infections Malaria Journal 10:56
Obbard DJ, Welch JJ, Little TJ (2009) Inferring selection in the Anopheles gambiae species complex: an example from immune-related serine protease inhibitors. Malaria Journal 8:117.
Obbard DJ, Callister D, Jiggins FM, Soares D, Yan G, Little TJ (2008) The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae. BMC Evolutionary Biology 8:174
Obbard DJ, Linton Y-M, Jiggins FM, Yan G, Little TJ (2007). Population genetics of Plasmodium resistance genes in Anopheles gambiae: no evidence for strong selection.. Molecular Ecology 16: 3497-3510
Mercurialis
Pujol B, Obbard DJ, Pannell JR, (2010) Symptoms of population range expansion: lessons from phenotypic and genetic differentiation in hexaploid Mercurialis annua. Plant Ecology & Diversity. 3(2) 103-108.
Obbard DJ, Harris SA, Buggs RJA, Pannell JR (2006). Hybridisation, polyploidy and the evolution of sexual systems in Mercurialis (Euphorbiaceae). Evolution 60:9 1801-1815.
Obbard DJ, Harris SA, Pannell JR (2006). Simple allelic-phenotype diversity and differentiation statistics for allopolyploids. Heredity 97 296-303. FD
Obbard DJ, Pannell JR, Harris SA (2006). Mercurialis canariensis (Euphorbiaceae), a new endemic to the Canary Islands. Kew Bulletin 61: 99-106.
Obbard DJ, Harris SA, Pannell JR (2006). Sexual systems and population genetic structure in an annual plant: testing the metapopulation model. American Naturalist 167:354-366. Opinion
Obbard DJ (2004). PhD Thesis
Reviews and Meta-analyses
Wang Y, Obbard DJ (2023). Experimental estimates of germline mutation rate in eukaryotes: a phylogenetic meta-analysis [Meta-analysis] Evolution Letters, qrad027 [bioRxiv from 25th January 2023]
Obbard DJ (2018). Expansion of the Metazoan Virosphere: Progress, Pitfalls, and Prospects. [Review] Current Opinion in Virology, 31:17-23 [Preprint from 21st May 2018].
Obbard DJ, Dudas G (2014). The genetics of host-virus coevolution in invertebrates [Review] Current Opinion in Virology 8:73-78
Lewis SH, Obbard DJ (2014). Recent insights into the evolution of innate viral sensing in Animals [Review] Current Opinion in Microbiology 20:170-175
Obbard DJ, Gordon KHJ, Buck AH, Jiggins FM (2009) The evolution of RNAi as a defence against viruses and transposable elements. [Review] Philosophical Transactions of the Royal Society Series B 364 99-115.
Pannell JR, Obbard DJ, Buggs RJA (2004). Polyploidy and the sexual system: what can we learn from Mercurialis annua? [Review] Biological Journal of the Linnean Society 82: 547-560.
Commentaries (Not necessarily peer-reviewed)
Dudas G, Obbard DJ (2015). Are arthropods at the heart of virus evolution? [Commentary] eLife 2015;4:e06837
Obbard DJ, Finnegan DJ (2008). RNA interference: Endogenous siRNAs derived from transposable elements. [Commentary] Current Biology 18: R561-R563
Pannell JR, Obbard DJ (2003). Probing the primacy of the patch: what makes a metapopulation? [Commentary] Journal of Ecology 91: 485-488.
Data Notes
Obbard DJ, Wellcome Sanger Institute Tree of Life programme, Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective et al. The genome sequence of a drosophilid fruit fly, Drosophila helvetica Burla 1948 Wellcome Open Research 2024, 9:418
Obbard DJ, Wellcome Sanger Institute Tree of Life programme, Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective et al. The genome sequence of a drosophilid fruit fly, Drosophila limbata von Roser 1840 Wellcome Open Research 2024, 9:365
Obbard DJ, Wellcome Sanger Institute Tree of Life programme, Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective et al. The genome sequence of the drosophilid fruit fly, Drosophila phalerata (Meigen, 1830) Wellcome Open Research 2024, 9:63
Obbard DJ, Wellcome Sanger Institute Tree of Life programme, Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective et al. The genome sequence of a drosophilid fruit fly, Drosophila histrio (Meigen, 1830) Wellcome Open Research 2024, 9:56
Obbard DJ, Wellcome Sanger Institute Tree of Life programme, Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective et al. The genome sequence of a drosophilid fruit fly, Chymomyza fuscimana (Drosophilidae) (Zetterstedt, 1838) Wellcome Open Research 2023, 8:477
Obbard DJ, Wellcome Sanger Institute Tree of Life programme, Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective et al. The genome sequence of a drosophilid fruit fly, Drosophila funebris (Fabricius, 1789) Wellcome Open Research 2023, 8:437
Obbard DJ, Wellcome Sanger Institute Tree of Life programme, Wellcome Sanger Institute Scientific Operations: DNA Pipelines collective et al. The genome sequence of a drosophilid fruit fly, Hirtodrosophila cameraria (Haliday, 1833) Wellcome Open Research 2023, 8:361
Other Collaborations
Jones JE, Court R, Kageyama D, Obbard DJ, Hurst GDD (bioRxiv) Variable prevalence of protective Spiroplasma infection over time in two natural populations of Drosophila hydei bioRxiv Preprint.
Feord HK, Dear FEG, Obbard DJ, van Ooijen G (2019). A magnesium transport protein related to mammalian SLC41 and bacterial MgtE contributes to circadian timekeeping in a unicellular green alga Genes 2019, 10(2), 158
Ramiro RS, Khan SM, Franke-Fayard B, Janse CJ, Obbard DJ, Reece SE, (2015). Hybridisation and pre-zygotic reproductive barriers in Plasmodium Proceedings of the Royal Society B 282: 20143027
Ramiro RS, Reece SE, Obbard DJ,(2012). Molecular evolution and phylogenetics of rodent malaria parasites. BMC Evolutionary Biology 12:219
Moore JC, Obbard DJ, Reuter C, West SA, Cook JM (2009) Male morphology and dishonest signalling in a fig wasp. Animal Behaviour 78: 147-153.
Moore JC, Obbard DJ, Reuter C, West SA, Cook JM (2008) Fighting strategies in two species of fig wasps. Animal Behaviour 76: 315-322.